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APC Polyclonal Antibody

CAT: 0866-RD217831A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD217831A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Description
This is a APC Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Adenomatous Polyposis Coli, Adenomatous polyposis coli protein, Apc, APC, CC1, Deleted in polyposis 2.5, DP2, DP2.5, DP3, FAP, FPC, GS, Protein APC
Swiss Prot
P25054
Accession Number
NP000029
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human APC
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.1 mg/mL
Dilution
IHC 1:40-1:200, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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