PE/Cyanine5.5 Anti-Mouse CD45 Antibody

• Background:

  CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

• Description:

  This is a PE/Cyanine5.5 Anti-Mouse CD45 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Receptor-type tyrosine-protein phosphatase C, Ptprc, L-CA, Ly-5, T200, CD45

• Gene ID:

  19264

• Swiss Prot:

  P06800

• Reactivity:

  Mouse

• Clonality:

  Monoclonal

• Conjugation:

  PE/Cyanine5.5

• Type:

  Flow Cytometry Antibody

• Applications:

  FC

• Assay Type:

  Antibody

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.05% Proclin300, 1% BSA

• Storage Conditions:

  Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

• Host or Source:

  Rat

• Isotype:

  Rat IgG2b, κ