FITC Anti-Mouse CD279/PD-1 Antibody

• Background:

  CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2) . It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

• Description:

  This is a FITC Anti-Mouse CD279/PD-1 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  PD-1, Programmed Death-1

• Gene ID:

  18566

• Swiss Prot:

  Q02242

• Reactivity:

  Mouse

• Clonality:

  Monoclonal

• Conjugation:

  FITC

• Type:

  Flow Cytometry Antibody

• Applications:

  FC

• Assay Type:

  Antibody

• Concentration:

  0.5 mg/mL

• Buffer:

  PBS with 0.05% Proclin300, 1% BSA

• Storage Conditions:

  Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

• Host or Source:

  Rat

• Isotype:

  Rat IgG2a, κ