PerCP/Cyanine5.5 Anti-Mouse CD49b Antibody

• Background:

  DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection) . DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

• Description:

  This is a PerCP/Cyanine5.5 Anti-Mouse CD49b Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, GPIa, VLA-2 subunit alpha, CD49b

• Gene ID:

  16398

• Swiss Prot:

  Q62469

• Reactivity:

  Mouse

• Clonality:

  Monoclonal

• Conjugation:

  PerCP/Cyanine5.5

• Type:

  Flow Cytometry Antibody

• Applications:

  FC

• Assay Type:

  Antibody

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.05% Proclin300, 1% BSA

• Storage Conditions:

  Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

• Host or Source:

  Rat

• Isotype:

  Rat IgM, κ