Trypsin-2 Human Recombinant Protein

CAT: 0519-PROTP07478-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0519-PROTP07478-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Recombinant Human Trypsin-2 expressed in E. coli having an Mw of 24kDa is purified by standard chromatography techniques. Applications: Trypsin digestion: the suggested ratio is 1:50 to 1:1000 (w/w) .

Synonyms

Trypsin-2;3.4.21.4; Anionic trypsinogen; Serine protease 2; Trypsin II; PRSS2; TRY2; TRYP2

Gene Name

PRSS2

UniProt

P07478

Reactivity

Human

Tissue Specificity

Expressed in Paneth cells, at the base of small intestinal crypts.

Source

Escherichia coli

Purification

Greater than 90% as determined by SDS-PAGE.

Bioactivity

2,800 units/mg.

Form

Sterile Filtered lyophilized powder.

Reconstitution

It is recommended to reconstitute the lyophilized Human Trypsin in sterile 1mM HCl or 50mM HAC not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Function

In the ileum, may be involved in defensin processing, including DEFA5.

Shipping Conditions

Available

Storage Conditions

Recombinant Human Trypsin although stable at room temp for 1 week, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.

Other Gene Names

Trypsin-2

Subcellular Location

Secreted, extracellular space.

UniProtKB · P07478

Trypsin-2

TRY2_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P07478
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: PRSS2
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 3.4.21.4
Processing: Precursor
Secondary accessions: —

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Ligand

CalciumMetal-binding

Biological process

Digestion

PTM

Disulfide bondSulfationZymogen

Molecular function

HydrolaseProteaseSerine protease

Cellular component

Secreted

Domain

Signal

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