Anti-PBRM1 Antibody (C-term)

• Background:

  Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) . Acts as a negative regulator of cell proliferation.

• Description:

  Boster Bio Anti-PBRM1 Antibody (C-term) (Catalog # M01130-1) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

• Synonyms:

  Protein polybromo-1, hPB1, BRG1-associated factor 180, BAF180, Polybromo-1D, PBRM1, BAF180, PB1

• Gene Name:

  PBRM1

• UniProt:

  Q86U86

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This PBRM1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1121-1155 amino acids from the C-terminal region of human PBRM1.

• Clonality:

  Polyclonal

• Tissue Specificity:

  Widely expressed.

• Applications:

  WB

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Dilution:

  WB: 1:2000

• Function:

  Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) . Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF) . Acts as a negative regulator of cell proliferation.

• Molecular Weight:

  192948 Da

• Shipping Conditions:

  Available

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Fragment:

  Rabbit IgG

• Subcellular Location:

  Nucleus