Anti-Human-AHCTF1 (S1232) Antibody

• Background:

  Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis.

• Description:

  Boster Bio Anti-Human-AHCTF1 (S1232) Antibody (Catalog # A08604) . Tested in WB application (s) . This antibody reacts with Human.

• Synonyms:

  Protein ELYS, Embryonic large molecule derived from yolk sac, Protein MEL-28, Putative AT-hook-containing transcription factor 1, AHCTF1, ELYS, TMBS62

• Gene Name:

  AHCTF1

• UniProt:

  Q8WYP5

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1210-1260 amino acids from human.

• Clonality:

  Polyclonal

• Applications:

  WB

• Field of Research:

  Cardiovascular, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Dilution:

  WB: 1:1000

• Function:

  Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis.

• Molecular Weight:

  252498 Da

• Shipping Conditions:

  Available

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Fragment:

  Rabbit IgG

• Subcellular Location:

  Cytoplasm {ECO:0000250|UniProtKB:Q8CJF7}. Nucleus. Nucleus envelope Nucleus matrix. Chromosome, centromere, kinetochore Nucleus, nucleoplasm. Nucleus, nuclear pore complex. Note=Localizes to the nuclear pore complex (NPC) throughout interphase. Localizes to the kinetochore from prophase, and this appears to require the Nup107-160 subcomplex of the NPC. Localizes to the periphery of chromatin from late anaphase.