Anti-IMPA1 Antibody

CAT: 0519-M05882-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0519-M05882-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo- inositol monophosphates, myo-inositol 1,3-diphosphate, myo- inositol 1,4-diphosphate, scyllo-inositol-phosphate, D-galactose 1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1- phosphate, beta-glycerophosphate, and 2'-AMP as substrates.

Description

Boster Bio Anti-IMPA1 Antibody (Catalog # M05882) . Tested in WB application (s) . This antibody reacts with Human.

Synonyms

Inositol monophosphatase 1, IMP 1, IMPase 1, 3.1.3.25, D-galactose 1-phosphate phosphatase, 3.1.3.94, Inositol-1 (or 4) -monophosphatase 1, Lithium-sensitive myo-inositol monophosphatase A1, IMPA1, IMPA

Gene Name

IMPA1

UniProt

P29218

Host

Mouse

Reactivity

Human

Immunogen

This IMPA1 antibody is generated from a mouse immunized with a recombinant protein from the human region of human IMPA1.

Clonality

Monoclonal

Clone

Clone: 2177CT172.34.52

Applications

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Dilution

WB: 1:1000-1:2000

Function

Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo-inositol monophosphates, myo-inositol 1,3-diphosphate, myo-inositol 1,4- diphosphate, scyllo-inositol-phosphate, D-galactose 1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta- glycerophosphate, and 2'-AMP as substrates.

Molecular Weight

30189 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Fragment

IgG1, κ

Subcellular Location

Cytoplasm.

Prediction Reactivity

Human

UniProtKB · P29218

Inositol monophosphatase 1

IMPA1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P29218
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: IMPA1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: IMP 1, IMPase 1
EC number: 3.1.3.25
Processing: —
Secondary accessions: B2R733, B4DLN3, B7Z6Q4, J3KQT7, Q9UK71

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cytoplasm

Molecular function

Hydrolase

Disease

Intellectual disability

Ligand

LithiumMagnesiumMetal-binding

PTM

Phosphoprotein

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