CXCL16 Mouse Recombinant Protein

• Description:

  CXCL16 Mouse Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 88 amino acids and having a molecular mass of 9.9kDa. The CXCL16 is purified by proprietary chromatographic techniques.

• Synonyms:

  C-X-C motif chemokine 16; Small-inducible cytokine B16; Transmembrane chemokine CXCL16; Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; SR-PSOX; Cxcl16; Srpsox; Zmynd15; AV290116; BB024863; 0910001K24Rik

• Gene Name:

  CXCL16

• UniProt:

  Q8BSU2

• Reactivity:

  Mouse

• Tissue Specificity:

  Widely expressed. Not detected in purified B- and T-cells.

• Source:

  Escherichia coli

• Sequence:

  [object Object]

• Purification:

  Greater than 97.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.

• Bioactivity:

  Determined by its ability to chemoattract murine lymphocytes using a concentration range of 100-1000ng/ml corresponding to a Specific Activity of 1,000-10,000IU/mg.

• Form:

  Sterile Filtered White lyophilized (freeze-dried) powder.

• Reconstitution:

  It is recommended to reconstitute the lyophilized CXCL16 Mouse in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

• Function:

  Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Also acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis.

• Shipping Conditions:

  Available

• Storage Conditions:

  Lyophilized CXCL16 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL16 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Please prevent freeze-thaw cycles.

• Other Gene Names:

  C-X-C motif chemokine 16

• Subcellular Location:

  Membrane