GLRX1 Glutaredoxin 1 Yeast Recombinant Protein

• Description:

  Glutaredoxin Saccharamyces cerevisiae Recombinant containing 6x His tag at C-Terminus produced in E. coli is a single, non-glycosylated, Polypeptide chain having a molecular mass of 16 kDa.

• Synonyms:

  Thioltransferase; GRX; GLRX1; GRX1; GRX-1; GLRX-1; Glutathione-dependent oxidoreductase 1; Glutaredoxin 1

• Gene Name:

  GRX1

• UniProt:

  P25373

• Reactivity:

  Yeast

• Source:

  Escherichia coli

• Purification:

  Greater than 90% as determined by SDS-PAGE.

• Form:

  Sterile Filtered clear colorless solution.

• Function:

  Component of the glutathione system which performs several activities such as glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity. The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase. Required for resistance to reactive oxygen species (ROS) by directly reducing hydroperoxides and for the detoxification of ROS-mediated damage. GRX1 is less active as an oxidoreductase than GRX2.

• Shipping Conditions:

  Available

• Storage Conditions:

  1 week at 2-10°C. For long term store at -20 to -80°C.

• Other Gene Names:

  Glutaredoxin-1

• Subcellular Location:

  Cytoplasm