TNFR Tumor Necrosis Factor Receptor Mouse Recombinant Protein

• Description:

  TNFR Mouse Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 191 amino acids and having a molecular mass of 21.1kDa. The TNFR is purified by proprietary chromatographic techniques.

• Synonyms:

  Tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60; CD120a; Tnfrsf1a; Tnfr-1; Tnfr1; FPF; TNF-R; TNFAR; TNFRI; p55-R; TNFR60; Tnfr-2; TNF-R-I; TNF-R55; TNFRp55; TNF-alphaR1; TNFalpha-R1

• Gene Name:

  TNFRSF1A

• UniProt:

  P25118

• Reactivity:

  Mouse

• Source:

  Escherichia coli

• Sequence:

  [object Object]

• Purification:

  Greater than 97.0% as determined by SDS-PAGE.

• Bioactivity:

  50

• Form:

  Sterile Filtered White lyophilized (freeze-dried) powder.

• Reconstitution:

  It is recommended to reconstitute the lyophilized TNFR in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

• Function:

  Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate- specific cysteine proteases) mediating apoptosis (By similarity) .

• Shipping Conditions:

  Available

• Storage Conditions:

  Lyophilized TNFR although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution TNFR should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.

• Other Gene Names:

  Tumor necrosis factor receptor superfamily member 1A

• Subcellular Location:

  Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane