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Desmin Human Recombinant Protein

CAT: 0519-PROTP17661-01Size: 5 µgDry Ice: NoHazardous: No
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CAT#:0519-PROTP17661-01Size:5 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Desmin Human Recombinant having a calculated molecular mass of 53,539 Dalton, showing a 55kDa band on SDS-page, pI-5.16.
Synonyms
Desmin; DES; CSM1; CSM2; CMD1I; FLJ12025; FLJ39719; FLJ41013; FLJ41793
Gene Name
DES
UniProt
P17661
Reactivity
Human
Source
Escherichia coli
Purification
Greater than 95.0% as determined by SDS-PAGE.
Form
Sterile Filtered White lyophilized (freeze-dried) powder.
Reconstitution
It is recommended to reconstitute the lyophilized Desmin in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Function
Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures.
Shipping Conditions
Available
Storage Conditions
Lyophilized Desmin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Desmin should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Please prevent freeze-thaw cycles.
Other Gene Names
Desmin
Subcellular Location
Cytoplasm. Cell membrane, sarcolemma

UniProtKB · P17661

Desmin

DESM_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P17661
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DES
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q15787, Q549R7, Q549R8, Q549R9, Q8IZR1, Q8IZR6, Q8NES2, Q8NEU6, Q8TAC4, Q8TCX2, Q8TD99, Q9UHN5, Q9UJ80
Protein keywords

PTM

ADP-ribosylationMethylationPhosphoproteinUbl conjugation

Disease

CardiomyopathyDesmin-related myopathyDisease variantLimb-girdle muscular dystrophyMyofibrillar myopathy

Cellular component

Cell membraneCytoplasmIntermediate filamentMembraneNucleus

Domain

Coiled coil

Molecular function

Muscle protein

Technical term

Proteomics identificationReference proteome

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