Human, Thrombin Human Recombinant Protein, HEK

• Description:

  Recombinant Human Thrombin produced in HEK cells, having a total molecular weight of 36kDa. The Thrombin is purified by proprietary chromatographic techniques.

• Synonyms:

  Prothrombin; EC 3.4.21.5; Coagulation factor II; F2; PT; THPH1; RPRGL2

• Gene Name:

  F2

• UniProt:

  P00734

• Reactivity:

  Human

• Tissue Specificity:

  Expressed by the liver and secreted in plasma.

• Source:

  HEK

• Bioactivity:

  5396 NIH Units/mg. The activity was determined in NIH units by comparing to Sigma’s human plasma thrombin. Protein concentration was measured using E (0.1%) @280nm = 1.83.

• Form:

  Sterile Filtered colorless solution.

• Function:

  Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

• Shipping Conditions:

  Available

• Storage Conditions:

  Store frozen at -20°C to -80°C for long periods of time. Avoid multiple freeze-thaw cycles.

• Other Gene Names:

  Prothrombin

• Subcellular Location:

  Secreted, extracellular space.