IL-20 Interleukin-20 Mouse Recombinant Protein

• Description:

  Interleukin-20 Mouse Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing 152 amino acids and having a total molecular mass of 17,584 Dalton. The IL-20 is purified by proprietary chromatographic techniques.

• Synonyms:

  IL10D; ZCYTO10; IL-20; MGC96907; Four alpha helix cytokine Zcyto10

• Gene Name:

  IL20

• UniProt:

  Q9JKV9

• Reactivity:

  Mouse

• Source:

  Escherichia coli

• Sequence:

  [object Object]

• Purification:

  Greater than 95.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.

• Bioactivity:

  The biological activity was determined by measuring the dose dependent activation of STAT3 in human epidermal keratinocytes (HEK2a cells) . Significant STAT3 activation is observed with greater than 100ng/mL of Interleukin-20 recombinant mouse, corresponding to a specific activity of 10,000 units/mg of Interleukin-20 recombinant mouse.

• Form:

  Sterile Filtered White lyophilized (freeze-dried) powder.

• Reconstitution:

  It is recommended to reconstitute the lyophilized Interleukin-20 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

• Function:

  Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3.

• Shipping Conditions:

  Available

• Storage Conditions:

  Lyophilized Interleukin-20 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL20 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Please prevent freeze-thaw cycles.

• Other Gene Names:

  Interleukin-20

• Subcellular Location:

  Secreted.