Acrp30 Mouse, Adiponectin Mouse Recombinant Protein, Trimeric form

• Description:

  Trimeric form of Acrp30 Mouse was expressed in HEK293 cells. The cysteine 39 was replaced with alanine (C39A) 9. mAd-C39A can only form trimer, but not hexamer or HMW form.

• Synonyms:

  Acrp30; AdipoQ; GBP-28; APM-1; ACDC

• Gene Name:

  ADIPOQ

• UniProt:

  Q60994

• Reactivity:

  Mouse

• Tissue Specificity:

  Synthesized exclusively by adipocytes and secreted into plasma.

• Source:

  HEK293

• Purification:

  Acrp30 Mouse purity is greater than 95% as determined by SDS-PAGE.

• Form:

  Filtered white lyophilized (freeze-dried) powder.

• Reconstitution:

  Add deionized water to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

• Function:

  Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

• Shipping Conditions:

  Available

• Storage Conditions:

  Store lyophilized Acrp30 Mouse at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted Acrp30 Mouse can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

• Other Gene Names:

  Adiponectin

• Subcellular Location:

  Secreted.