FKBP5 FK506 Binding Protein 5 Human Recombinant Protein

• Description:

  FKBP5 Human Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain (Met1-Val457) containing 467 amino acids including a 10 aa His tag at N-terminus. The total calculated molecular mass is 52.5kDa.

• Synonyms:

  FK506 Binding Protein 5; 54 KDa Progesterone Receptor-Associated Immunophilin; 51 KDa FK506-Binding Protein; Androgen-Regulated Protein 6; HSP90-Binding Immunophilin; FK506-Binding Protein 5; PPIase FKBP5; 51 KDa FKBP; FF1 Antigen; EC 5.2.1.8; Rotamase; FKBP-51; FKBP51; FKBP54; AIG6; P54; Peptidylprolyl Cis-Trans Isomerase; T-Cell FK506-Binding Protein; PPIASE; Ptg-10; FKBP-5; FKBP5

• Gene Name:

  FKBP5

• UniProt:

  Q13451

• Reactivity:

  Human

• Tissue Specificity:

  Widely expressed, enriched in testis compared to other tissues.

• Source:

  Escherichia coli

• Sequence:

  [object Object]

• Purification:

  Greater than 90.0% as determined by SDS-PAGE.

• Form:

  Filtered White lyophilized (freeze-dried) powder.

• Reconstitution:

  Prepare about 0.5mg/ml working stock solution with deionized water and let the lyophilized pellet dissolve completely. Filter sterilize your culture media/working solutions containing this non-sterile FKBP5 before using in cell culture.

• Function:

  Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90) . Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded.

• Shipping Conditions:

  Available

• Storage Conditions:

  Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

• Other Gene Names:

  Peptidyl-prolyl cis-trans isomerase FKBP5

• Subcellular Location:

  Cytoplasm. Nucleus.