MCP-3 Monocyte Chemotactic Protein-3 Mouse Recombinant Protein (CCL7)

• Description:

  Monocyte Chemotactic Protein-3 Mouse Recombinant produced in E. coli is a non-glycosylated, Polypeptide chain containing 74 amino acids and having a molecular mass of 8510 Dalton. The MCP-3 is purified by proprietary chromatographic techniques.

• Synonyms:

  Small inducible cytokine A7; CCL7; Monocyte chemotactic protein 3; MCP-3; Monocyte chemoattractant protein 3; NC28; chemokine (C-C motif) ligand 7; FIC; MARC; MCP3; SCYA6; SCYA7; MGC138463; MGC138465

• Gene Name:

  CCL7

• UniProt:

  Q03366

• Reactivity:

  Mouse

• Source:

  Escherichia coli

• Sequence:

  [object Object]

• Purification:

  Greater than 98.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.

• Bioactivity:

  The specific activity as determined by the ability of Mouse MCP-3 to chemoattract Balb/C mouse spleen MNCs at 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.

• Form:

  Sterile Filtered White lyophilized (freeze-dried) powder.

• Reconstitution:

  It is recommended to reconstitute the lyophilized Monocyte Chemotactic Protein-3 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

• Function:

  Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity (By similarity) .

• Shipping Conditions:

  Available

• Storage Conditions:

  Lyophilized MCP-3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL7 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.

• Other Gene Names:

  C-C motif chemokine 7

• Subcellular Location:

  Secreted.