FGF-8 Fibroblast Growth Factor-8 Human Recombinant Protein

• Description:

  FGF-8 Human Recombinant produced in HEK cells is a glycosylated monomer, having a molecular weight range of 30-45kDa due to glycosylation. The FGF8 is purified by proprietary chromatographic techniques.

• Synonyms:

  FGF8B; FGF-8B; FGF8-B; KAL6; HBGF-8; HBGF8; AIGF; HBGF-8; MGC149376; fibroblast growth factor 8

• Gene Name:

  FGF8

• UniProt:

  P55075

• Reactivity:

  Human

• Source:

  HEK

• Purification:

  Greater than 95% as obsereved by SDS-PAGE.

• Bioactivity:

  50

• Form:

  Sterile Filtered White lyophilized (freeze-dried) powder.

• Reconstitution:

  It is recommended to reconstitute the lyophilized FGF8 in sterile water containing 0.1% endotoxin-free recombinant HSA.

• Function:

  Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system (PubMed:16384934, PubMed:16597617, PubMed:8663044) . Plays a role in neurite outgrowth in hippocampal cells (PubMed:21576111) .

• Shipping Conditions:

  Available

• Storage Conditions:

  Lyophilized FGF-8 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FGF8 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.

• Other Gene Names:

  Fibroblast growth factor 8

• Subcellular Location:

  Secreted.