DLST Dihydrolipoamide S-Succinyltransferase Human Recombinant Protein

• Description:

  DLST is a Full-length cDNA coding for the mature form of the human OGDC-E2 protein having a molecular mass of 42,301 Dalton (pH 6.3) .DLST protein is fused to a hexa-histidine purification tag. Applications: Western blot with anti-M2-Antigen autoantibody-positive patient sera or monoclonal anti-hexa-His-tag antibody.

• Synonyms:

  Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) ; Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; component E2; DLST; E2K; OGDC-E2; EC 2.3.1.61; EC 2.3.1

• Gene Name:

  DLST

• UniProt:

  P36957

• Reactivity:

  Human

• Source:

  Sf9 insect cells

• Applications:

  WB

• Purification:

  DLST purity was found to be greater than 75% as determined by SDS-PAGE.

• Function:

  The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO (2) . It contains multiple copies of 3 enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) .

• Shipping Conditions:

  Available

• Storage Conditions:

  Store DLST at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.

• Other Gene Names:

  Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

• Subcellular Location:

  Mitochondrion.