CTSD Cathepsin-D Human Recombinant Protein

• Description:

  CTSD produced in HEK293 cells is a single, glycosylated polypeptide chain containing 398 amino acids (21-412 a.a.) and having a molecular mass of 43.4kDa. CTSD is expressed with an 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

• Synonyms:

  Cathepsin D; EC 3.4.23.5; CTSD; CPSD; CLN10; MGC2311

• Gene Name:

  CTSD

• UniProt:

  P07339

• Tissue Specificity:

  Expressed in the aorta extrcellular space (at protein level) .

• Source:

  HEK293

• Sequence:

  [object Object]

• Purification:

  Greater than 95% as determined by SDS-PAGE

• Form:

  Sterile Filtered clear solution.

• Function:

  Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

• Shipping Conditions:

  Available

• Storage Conditions:

  Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.Please prevent freeze-thaw cycles.

• Other Gene Names:

  Cathepsin D

• Subcellular Location:

  Lysosome. Melanosome. Secreted, extracellular space. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380) .