Mouse LI-Cadherin-17 CDH17 ELISA Kit PicoKine®, Carrier-free

• Background:

  Cadherin-17 is a protein that in humans is encoded by the CDH17 gene. It is mapped to 4; 4 A1. This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine.

• :

  heparin

• Description:

  Mouse LI-Cadherin-17 CDH17 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse CDH17 in cell culture supernatants, serum and plasma (heparin) . Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

• Reproducibility:

  Lots	Lot 1 (pg/ml)	Lot 2 (pg/ml)	Lot 3 (pg/ml)	Lot 4 (pg/ml)	Mean (pg/ml)	Standard Deviation	CV (%)
  Sample 1	90	87	79	82	84	4.27	5.0%
  Sample 2	369	386	427	423	401	24.53	6.1%
  Sample 3	1459	1399	1340	1383	1395	42.66	3.0%

  *number of samples for each test n=16.

• Synonyms:

  Cadherin-17; BILL-cadherin; Liver-intestine cadherin; LI-cadherin; P130; Cdh17

• Gene Name:

  cadherin 17

• Gene ID:

  12557

• UniProt:

  Q9R100

• Reactivity:

  Mouse

• Cross Reactivity:

  There is no detectable cross-reactivity with other relevant proteins.

• Immunogen:

  Expression system for standard: NS0; Immunogen sequence: F26-S827

• Tissue Specificity:

  Highest expression is found in intestine with lower expression in spleen, bone marrow, lung and testis. No expression detected in liver, kidney, heart, brain or skeletal muscle. Expressed in precursor B-cells and myeloid cells.

• Applications:

  ELISA

• Standard:

  3 ng/tube

• Sample Type:

  cell culture supernatants, serum and plasma (heparin)

• Detection Range:

  46.9 pg/ml - 3,000 pg/ml

• Sensitivity:

  <10 pg/ml

• Function:

  Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine.

• Components:

  Description|Quantity Pre-coated 96-well strip microplate|1 Standard|2 vials Biotinylated antibody (100x)|100ul Avidin-Biotin-Peroxidase Complex (100x)|100ul Sample Diluent|30ml Antibody Diluent|12ml Avidin-Biotin-Peroxidase Diluent|12ml Color Developing Reagent (TMB)|10ml Stop Solution|10ml Wash Buffer (25x)|20ml Adhesive plate sealers|4

• Storage Conditions:

  Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

• Specificity:

  Natural and recombinant mouse Cadherin-17

• Subcellular Location:

  Cell membrane. Single-pass type I membrane protein.