Human TNFRSF19/TROY ELISA Kit PicoKine®, Carrier-free

• Background:

  Tumor necrosis factor receptor superfamily, member 19, also known as TNFRSF19 and TROY, is a human gene. It is mapped to 13q12.11-q12.3. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described.

• :

  heparin or EDTA

• Description:

  Human TNFRSF19/TROY ELISA Kit PicoKine® (96 Tests). Quantitate Human TNFRSF19 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 12pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

• Reproducibility:

  Lots	Lot 1 (pg/ml)	Lot 2 (pg/ml)	Lot 3 (pg/ml)	Lot 4 (pg/ml)	Mean (pg/ml)	Standard Deviation	CV (%)
  Sample 1	184	205	190	190	192	7.75	4%
  Sample 2	541	552	500	518	527	20.17	3.8%
  Sample 3	1334	1468	1351	1411	1391	52.86	3.8%

  *number of samples for each test n=16.

• Synonyms:

  Tumor necrosis factor receptor superfamily member 19;TRADE;Toxicity and JNK inducer;TNFRSF19;TAJ, TROY;UNQ1888/PRO4333;

• Gene Name:

  Tumor necrosis factor receptor superfamily member 19

• Gene ID:

  55504

• UniProt:

  Q9NS68

• Reactivity:

  Human

• Cross Reactivity:

  There is no detectable cross-reactivity with other relevant proteins.

• Immunogen:

  Expression system for standard: NS0; Immunogen sequence: E30-L170

• Tissue Specificity:

  Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes.

• Applications:

  ELISA

• Standard:

  10 ng/tube

• Sample Type:

  cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

• Detection Range:

  62.5 pg/ml - 4,000 pg/ml

• Sensitivity:

  <12 pg/ml

• Function:

  Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death.

• Components:

  Description|Quantity Pre-coated 96-well strip microplate|1 Standard|2 vials Biotinylated antibody (100x)|100ul Avidin-Biotin-Peroxidase Complex (100x)|100ul Sample Diluent|30ml Antibody Diluent|12ml Avidin-Biotin-Peroxidase Diluent|12ml Color Developing Reagent (TMB)|10ml Stop Solution|10ml Wash Buffer (25x)|20ml Adhesive plate sealers|4

• Storage Conditions:

  Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

• Calculated Molecular Weight:

  46015 MW

• Specificity:

  Natural and recombinant human TNFRSF19

• Subcellular Location:

  Membrane ; Single-pass type I membrane protein .

• Protein Name:

  Tumor necrosis factor receptor superfamily member 19