Mouse TNFRSF13C/BAFFR ELISA Kit PicoKine®, Carrier-free

• Background:

  Tumor necrosis factor receptor superfamily member 13C also known as B-cell-activating factor receptor or BAFF receptor is a protein that in humans is encoded by the TNFRSF13C gene. By homology to a BAC clone, the BAFFR gene was mapped to chromosome 22q13.1-q13.31. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular phenylalanine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

• :

  heparin or EDTA

• Description:

  Mouse TNFRSF13C/BAFFR ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Tnfrsf13c in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

• Reproducibility:

  Lots	Lot 1 (pg/ml)	Lot 2 (pg/ml)	Lot 3 (pg/ml)	Lot 4 (pg/ml)	Mean (pg/ml)	Standard Deviation	CV (%)
  Sample 1	110	112	109	105	109	2.54	2.3%
  Sample 2	605	673	577	616	617	34.92	5.6%
  Sample 3	2620	2839	2527	2525	2627	127.86	4.8%

  *number of samples for each test n=16.

• Synonyms:

  Tumor necrosis factor receptor superfamily member 13C;B-cell maturation defect;B-cell-activating factor receptor;BAFF receptor;BAFF-R;BLyS receptor 3;CD268;Tnfrsf13c;Baffr, Bcmd, Br3;

• Gene Name:

  Tumor necrosis factor receptor superfamily member 13C

• Gene ID:

  72049

• UniProt:

  Q9D8D0

• Reactivity:

  Mouse

• Cross Reactivity:

  There is no detectable cross-reactivity with other relevant proteins.

• Immunogen:

  Expression system for standard: NS0; Immunogen sequence: S10-A71

• Tissue Specificity:

  Highly expressed in spleen and testis; detected at lower levels in lung and thymus.

• Applications:

  ELISA

• Standard:

  10 ng/tube

• Sample Type:

  cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

• Detection Range:

  78 pg/ml - 5,000 pg/ml

• Sensitivity:

  <10 pg/ml

• Function:

  B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. .

• Components:

  Description|Quantity Pre-coated 96-well strip microplate|1 Standard|2 vials Biotinylated antibody (100x)|100ul Avidin-Biotin-Peroxidase Complex (100x)|100ul Sample Diluent|30ml Antibody Diluent|12ml Avidin-Biotin-Peroxidase Diluent|12ml Color Developing Reagent (TMB)|10ml Stop Solution|10ml Wash Buffer (25x)|20ml Adhesive plate sealers|4

• Storage Conditions:

  Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

• Calculated Molecular Weight:

  18798 MW

• Specificity:

  Natural and recombinant mouse TNFRSF13C

• Subcellular Location:

  Membrane ; Single-pass type III membrane protein .

• Protein Name:

  Tumor necrosis factor receptor superfamily member 13C