Anti-Pumilio 2 Rabbit Monoclonal Antibody, Carrier-free

• Description:

  Boster Bio Anti-Pumilio 2 Rabbit Monoclonal Antibody catalog # M03347. Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Steroid hormone receptor ERR1;Estrogen receptor-like 1;Estrogen-related receptor alpha;ERR-alpha;Nuclear receptor subfamily 3 group B member 1;ESRRA;ERR1, ESRL1, NR3B1;

• Gene Name:

  Steroid hormone receptor ERR1

• UniProt:

  Q8TB72

• Host:

  Rabbit

• Reactivity:

  Human,Mouse,Rat

• Immunogen:

  A synthesized peptide derived from human Pumilio 2

• Clonality:

  Monoclonal

• Clone:

  Clone: 23P75

• Tissue Specificity:

  Visceral organs specific expression. Strong expression was found in liver, kidney and intestine followed by spleen and to a lesser extent the adrenals.

• Applications:

  WB,ICC,IF,IP,Flow Cytometry

• Purification:

  Affinity-chromatography

• Concentration:

  Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Reconstitution:

  Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

• Function:

  Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle. .

• Components:

  Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

• Storage Conditions:

  Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  45510 MW

• Observed Molecular Weight:

  114 kDa

• Fragment:

  IgG

• Applications Notes:

  WB 1:500-1:2000
  ICC/IF 1:50-1:200
  IP 1:20
  FC 1:50

• Subcellular Location:

  Nucleus .

• Protein Name:

  T-cell surface glycoprotein CD3 zeta chain