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Meconine

CAT: 0804-HY-W019151-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W019151-01Size:100 mg
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Description
Meconine is an endogenous metabolite of Noscapine. Meconine is the major metabolite in all three species, accounting for about 3, 8 and 2% of the dose in the first 24 h urines of rats, rabbits and humans, respectively. Meconine can be used as a marker to detect illicit opiate use[1][2][3].
CAS Number
569-31-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/meconine.html
Concentration
10mM
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1OCC2=C1C(OC)=C(OC)C=C2
Molecular Formula
C10H10O4
Molecular Weight
194.19
Precautions
H302, H315, H319, H335
References & Citations
[1]Tsunoda N, Yoshimura H. Metabolic fate of noscapine. II. Isolation and identification of novel metabolites produced by C-C bond cleavage. Xenobiotica. 1979 Mar;9 (3) :181-7. |[2]Yao Y, Xiong Y. Metabolic pathway profiling of the derivative of important herbal component noscapine. Eur J Drug Metab Pharmacokinet. 2016 Feb;41 (1) :27-32. |[3]Dinis-Oliveira RJ. Metabolism and metabolomics of opiates: A long way of forensic implications to unravel. J Forensic Leg Med. 2019 Feb;61:128-140.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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