Anti-Phospho-Histone H2B (T129) HIST1H2BC Rabbit Monoclonal Antibody, Carrier-free

• Description:

  Boster Bio Anti-Phospho-Histone H2B (T129) HIST1H2BC Rabbit Monoclonal Antibody catalog # P30930. Tested in WB application. This antibody reacts with Yeast.

• Phospho Site:

  T129

• Synonyms:

  Histone H2B.1;Suppressor of Ty protein 12;HTB1;H2B1, SPT12;YDR224C;YD9934.09C;

• Gene Name:

  Histone H2B.1

• UniProt:

  P02293

• Host:

  Rabbit

• Reactivity:

  Yeast

• Immunogen:

  A synthesized peptide derived from yeast Phospho-Histone H2B (T129)

• Clonality:

  Monoclonal

• Clone:

  Clone: DEI-8

• Tissue Specificity:

  Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.

• Applications:

  WB

• Purification:

  Affinity-chromatography

• Concentration:

  Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Function:

  Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. .

• Components:

  Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

• Storage Conditions:

  Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  14252 MW

• Observed Molecular Weight:

  140 kDa, 130 kDa, 110 kDa

• Fragment:

  Rabbit IgG

• Applications Notes:

  WB 1:500-1:1000

• Subcellular Location:

  Nucleus. Chromosome.

• Protein Name:

  Synapsin-1