MMC(TMZ)-TOC

MMC(TMZ)-TOC

• UNSPSC Description: MMC(TMZ)-TOC has high binding affinity and selectivity for somatostatin receptor subtype-2 (SSTR2). MMC(TMZ)-TOC targets delivery of TMZ to SSTR2-positive tumor cells[1].
• Target Antigen: Somatostatin Receptor
• Type: Peptides
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mmc-tmz-toc.html
• Solubility: 10 mM in DMSO
• Smiles: OC(CN1CCN(CC(N[C@H](CC2=CC=CC=C2)C(N[C@@H](CSSC[C@H](NC([C@@]([C@@H](C)O)([H])NC3=O)=O)C(N[C@@H]([C@@H](C)O)CO)=O)C(N[C@@H](CC4=CC=C(O)C=C4)C(N[C@@H](C(N[C@H]3CCCCN)=O)CC5=CC6=C(N5)C=CC=C6)=O)=O)=O)=O)CCN(CC(O)=O)CCN(C(CCNC(C7=C(N8C=N7)N=NN(C)C8=O)=O)=O)CC1)=O
• Molecular Weight: 1611.80
• References & Citations: [1]AghaAmiri S, et al. Somatostatin Receptor Subtype-2 Targeting System for Specific Delivery of Temozolomide. J Med Chem. 2024 Feb 22;67(4):2425-2437.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported