Anti-SLMAP Antibody Picoband®, iFluor647 Conjugate

• Background:

  Sarcolemmal membrane-associated protein is a protein that in humans is encoded by the SLMAP gene. This gene encodes a component of a conserved striatin-interacting phosphatase and kinase complex. Striatin family complexes participate in a variety of cellular processes including signaling, cell cycle control, cell migration, Golgi assembly, and apoptosis. The protein encoded by this gene is a coiled-coil, tail-anchored membrane protein with a single C-terminal transmembrane domain that is posttranslationally inserted into membranes. Mutations in this gene are associated with Brugada syndrome, a cardiac channelopathy. Alternative splicing results in multiple transcript variants.

• Description:

  Boster Bio Anti-SLMAP Antibody Picoband® catalog # A07262. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

• Synonyms:

  Interleukin-18-binding protein; IL-18BP; Interferon gamma-inducing factor-binding protein; Il18bp; Igifbp

• Gene Name:

  interleukin 18 binding protein

• Gene ID:

  7871

• UniProt:

  Q14BN4

• Host:

  Rabbit

• Reactivity:

  Human,Mouse

• Cross Reactivity:

  No cross-reactivity with other proteins.

• Immunogen:

  E.coli-derived human SLMAP recombinant protein (Position: D25-E607).

• Clonality:

  Polyclonal

• Tissue Specificity:

  Ubiquitous.

• Applications:

  WB,Flow Cytometry,ELISA

• Purification:

  Immunogen affinity purified.

• Concentration:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Form:

  Lyophilized

• Reconstitution:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Function:

  Binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response (By similarity). .

• Components:

  Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

• References & Citations:

  1. Wigle, J. T., Demchyshyn, L., Pratt, M. A. C., Staines, W. A., Salih, M., Tuana, B. S. Molecular cloning, expression, and chromosomal assignment of sarcolemmal-associated proteins: a family of acidic amphipathic alpha-helical proteins associated with the membrane. J. Biol. Chem. 272: 32384-32394, 1997.

• Storage Conditions:

  At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

• Calculated Molecular Weight:

  67166 MW

• Observed Molecular Weight:

  95 kDa

• Fragment:

  Rabbit IgG

• Applications Notes:

  Western blot, 0.25-0.5 μg/ml, Human, Mouse
  Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
  ELISA, 0.1-0.5 μg/ml, -
  

• Subcellular Location:

  Secreted.

• Protein Name:

  Suppressor of tumorigenicity 7 protein