Anti-Aldolase C/ALDOC Antibody Picoband®, iFluor647 Conjugate

• Background:

  Aldolase C, fructose-bisphosphate (ALDOC, or ALDC), is an enzyme that, in humans, is encoded by the ALDOC gene on chromosome 17. This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.

• Description:

  Boster Bio Anti-Aldolase C/ALDOC Antibody Picoband® catalog # A05296-1. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

• Synonyms:

  Loricrin; LOR; LRN

• Gene Name:

  loricrin

• Gene ID:

  230

• UniProt:

  P09972

• Host:

  Rabbit

• Reactivity:

  Human,Mouse,Rat

• Cross Reactivity:

  No cross-reactivity with other proteins.

• Immunogen:

  A synthetic peptide corresponding to a sequence at the N-terminus of human Aldolase C/ALDOC, which shares 100% and 93.8% amino acid (aa) sequence identity with mouse and rat ALDOC, respectively.

• Clonality:

  Polyclonal

• Tissue Specificity:

  Expressed in testis and to a lesser degree in brain, ovary and placenta. Found in most tissues at low levels.

• Applications:

  IHC,WB

• Purification:

  Immunogen affinity purified.

• Concentration:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Form:

  Lyophilized

• Reconstitution:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Function:

  Major keratinocyte cell envelope protein.

• Components:

  Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

• References & Citations:

  1. Buono, P., Paolella, G., Mancini, F. P., Izzo, P., Salvatore, F. The complete nucleotide sequence of the gene coding for the human aldolase C. Nucleic Acids Res. 16: 4733 only, 1988. 2. Rocchi, M., Vitale, E., Covone, A., Romeo, G., Santamaria, R., Buono, P., Paolella, G., Salvatore, F. Assignment of human aldolase C gene to chromosome 17, region cen--q21.1. Hum. Genet. 82: 279-282, 1989. 3. Rottmann, W. H., Deselms, K. R., Niclas, J., Camerato, T., Holman, P. S., Green, C. J., Tolan, D. R. The complete amino acid sequence of the human aldolase C isozyme derived from genomic clones. Biochimie 69: 137-145, 1987.

• Storage Conditions:

  At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

• Calculated Molecular Weight:

  39411 MW

• Observed Molecular Weight:

  39 kDa

• Fragment:

  Rabbit IgG

• Applications Notes:

  Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
  Immunohistochemistry, 2-5 μg/ml, Rat
  

• Subcellular Location:

  Nucleoplasm. Cytoplasm.

• Protein Name:

  Zinc finger protein Helios