Anti-Golm1/GOLPH2 Antibody Picoband®, APC Conjugate

• Background:

  The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi transmembrane protein. It processes proteins synthesized in the rough endoplasmic reticulum and assists in the transport of protein cargo through the Golgi apparatus. The expression of this gene has been observed to be upregulated in response to viral infection. Alternatively spliced transcript variants encoding the same protein have been described for this gene.

• Description:

  Boster Bio Anti-Golm1/GOLPH2 Antibody Picoband® catalog # A02975-2. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

• Synonyms:

  Cerebellar degeneration-related protein 2; Major Yo paraneoplastic antigen; Paraneoplastic cerebellar degeneration-associated antigen; CDR2; PCD17

• Gene Name:

  cerebellar degeneration related protein 2

• Gene ID:

  105348

• UniProt:

  Q91XA2

• Host:

  Rabbit

• Reactivity:

  Mouse,Rat

• Cross Reactivity:

  No cross-reactivity with other proteins.

• Immunogen:

  E.coli-derived mouse Golm1/GOLPH2 recombinant protein (Position: S37-A393).

• Clonality:

  Polyclonal

• Tissue Specificity:

  Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.

• Applications:

  ELISA,Flow Cytometry,IF,IHC,ICC,WB

• Purification:

  Immunogen affinity purified.

• Concentration:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Form:

  Lyophilized

• Reconstitution:

  Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

• Function:

  Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity). .

• Components:

  Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

• References & Citations:

  1. Kladney, R. D., Bulla, G. A., Guo, L., Mason, A. L., Tollefson, A. E., Simon, D. J., Koutoubi, Z., Fimmel, C. J. GP73, a novel Golgi-localized protein upregulated by viral infection. Gene 249: 53-65, 2000.

• Storage Conditions:

  Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  51855 MW

• Observed Molecular Weight:

  73 kDa

• Fragment:

  Rabbit IgG

• Applications Notes:

  Western blot, 0.1-0.25μg/ml, Mouse, Rat
  Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Mouse, Rat
  Immunocytochemistry/Immunofluorescence, 5μg/ml, Mouse
  Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Mouse
  ELISA, 0.1-0.5μg/ml, -
  

• Subcellular Location:

  Cytoplasm.

• Protein Name:

  Cerebellar degeneration-related protein 2