Anti-alpha 1 Antitrypsin/SERPINA1 Antibody Picoband® (FITC Conjugate)

• Background:

  SERPINA1 is also known as PI, A1A or AAT. The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.

• Description:

  Boster Bio Anti-alpha 1 Antitrypsin/SERPINA1 Antibody Picoband® catalog # PB9354. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

• Synonyms:

  Alpha-1-antiproteinase;Alpha-1-antitrypsin;Alpha-1-proteinase inhibitor;Serpin A1;Serpina1;

• Gene Name:

  Alpha-1-antiproteinase

• UniProt:

  P17475

• Host:

  Rabbit

• Reactivity:

  Mouse,Rat

• Cross Reactivity:

  No cross-reactivity with other proteins.

• Immunogen:

  E.coli-derived rat SERPINA1 recombinant protein (Position: K211-R411). Rat SERPINA1 shares 66% amino acid (aa) sequence identity with human SERPINA1.

• Clonality:

  Polyclonal

• Tissue Specificity:

  Plasma. .

• Applications:

  IHC,WB

• Purification:

  Immunogen affinity purified.

• Concentration:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Form:

  Lyophilized

• Reconstitution:

  Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

• Function:

  Inhibitor of serine proteases. The primary target is elastase, but also has a moderate affinity for plasmin and thrombin.

• Storage Conditions:

  Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

• Fragment:

  Rabbit IgG

• Applications Notes:

  Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Mouse, Rat, By Heat
  Western blot, 0.1-0.5μg/ml, Mouse, Rat
  

• Subcellular Location:

  Secreted.

• Sequence Similarities:

  Belongs to the semaphorin family.

• Protein Name:

  Alpha-1-antiproteinase