Anti-Apolipoprotein D/APOD Antibody Picoband®, HRP Conjugate

• Background:

  Apolipoprotein D (Apo-D) is a protein that in humans, encoded by the APOD gene. Being a member of the alpha (2 mu)-microglobulin superfamily of carrier proteins, Apo-D is also known as lipocalin.The gene has been localized to the p14.2----qter region of human chromosome 3. It is a glycoprotein of estimated molecular weight 33,000 Da. The Apo-D encoded a protein of 169 amino acid residue.It has been detected in human liver, intestine, pancreas, kidney, placenta, adrenal, spleen, and fetal brain tissue. For its features, Apo-D has been a biomarker of androgen insensitivity syndrome (AIS).

• Description:

  Boster Bio Anti-Apolipoprotein D/APOD Antibody catalog # PA1388. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

• Synonyms:

  Apolipoprotein D;Apo-D;ApoD;APOD;

• Gene Name:

  Apolipoprotein D

• UniProt:

  P05090

• Host:

  Rabbit

• Reactivity:

  Human

• Cross Reactivity:

  No cross-reactivity with other proteins

• Immunogen:

  A synthetic peptide corresponding to a sequence at the C-terminus of human Apolipoprotein D.

• Clonality:

  Polyclonal

• Tissue Specificity:

  Expressed in liver, intestine, pancreas, kidney, placenta, adrenal, spleen, fetal brain tissue and tears.

• Applications:

  WB

• Purification:

  Immunogen affinity purified.

• Concentration:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Form:

  Lyophilized

• Reconstitution:

  Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

• Function:

  APOD occurs in the macromolecular complex with lecithin- cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.

• Components:

  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

• References & Citations:

  1. Drayna, D. T., McLean, J. W., Wion, K. L., Trent, J. M., Drabkin, H. A., Lawn, R. M. Human apolipoprotein D gene: gene sequence, chromosome localization, and homology to the alpha-2mu-globulin superfamily. DNA 6: 199-204, 1987. 2. Drayna, D., Fielding, C., McLean, J., Baer, B., Castro, G., Chen, E., Comstock, L., Henzel, W., Kohr, W., Rhee, L., Wion, K., Lawn, R.Cloning and expression of human apolipoprotein D cDNA.J. Biol. Chem.261: 16535-16539, 1986. 3. Appari M, Werner R, Wünsch L, Cario G, Demeter J, Hiort O, Riepe F, Brooks JD, Holterhus PM (June 2009). "Apolipoprotein D (APOD) is a putative biomarker of androgen receptor function in androgen insensitivity syndrome". J. Mol. Med. 87 (6): 623–32.

• Storage Conditions:

  Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  21276 MW

• Observed Molecular Weight:

  30 kDa

• Fragment:

  Rabbit IgG

• Specificity:

  No cross reactivity with other proteins.

• Applications Notes:

  Western blot, 0.1-0.5μg/ml, Human
  

• Subcellular Location:

  Secreted.

• Sequence Similarities:

  Belongs to the short-chain dehydrogenases/reductases (SDR) family.

• Protein Name:

  Apolipoprotein D(Apo-D/ApoD)