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Raffinose

CAT: 0804-HY-N7088-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N7088-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Raffinose (Melitose) regulates intestinal flora, inhibits TLR4-MyD88-NF-κB signaling pathway, and activates Nrf2 signaling pathway. Raffinose exhibits anti-inflammatory, antioxidant, and immunomodulatory activities. Raffinose is orally active[1][2][3].
CAS Number
512-69-6
Product Name Alternative
Melitose
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; Keap1-Nrf2; MyD88; NF-κB; Toll-like Receptor (TLR)
Type
Natural Products
Related Pathways
Autophagy; Immunology/Inflammation; NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/raffinose.html
Concentration
10mM
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 250 mg/mL (ultrasonic)
Smiles
OC[C@]1(O[C@H](CO)[C@@H](O)[C@@H]1O)O[C@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)CO[C@H]3O[C@@H]([C@H](O)[C@H](O)[C@H]3O)CO
Molecular Formula
C18H32O16
Molecular Weight
504.44
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhang P, et al., Raffinose Ameliorates DSS-Induced Colitis in Mice by Modulating Gut Microbiota and Targeting the Inflammatory TLR4-MyD88-NF-κB Signaling Pathway. Foods. 2024 Jun 13;13 (12) :1849. |[2]Lin S, et al., Raffinose increases autophagy and reduces cell death in UVB-irradiated keratinocytes. J Photochem Photobiol B. 2019 Dec;201:111653. |[3]Liu J, et al., Targeting antioxidant factor Nrf2 by raffinose ameliorates lipid dysmetabolism-induced pyroptosis, inflammation and fibrosis in NAFLD. Phytomedicine. 2024 Jul 25;130:155756.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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