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Recombinant Human Interleukin-6 (IL6) (Active)

CAT: 0013-GTR19063870-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19063870-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This Recombinant Human Interleukin-6 (IL6) (Active) spans the amino acid sequence from region 30-212aa. Purity: Greater than 95% as determined by SDS-PAGE.
Product Name Alternative
Interleukin-6; IL-6; B-Cell Stimulatory Factor 2; BSF-2; CTL Differentiation Factor; CDF; Hybridoma Growth Factor; Interferon Beta-2; IFN-Beta-2; IL6; IFNB2
UniProt
P05231
Expression Region
30-212aa
Tag
Tag free
Source
Mammalian cell
Origin
Homo sapiens (Human)
Field of Research
Immunology & Inflammation
Endotoxin
≤10 EU/mg by the LAL method
Purity
Greater than 95% as determined by SDS-PAGE.
Bioactivity
Measured in a cell proliferation assay using M-NSF-60 cells. The ED50 for this effect is 0.2-1 ng/mL.
Form
Lyophilized powder
Molecular Weight
20.8 kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
For research use only.
Applications Notes
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Preservative
Lyophilized from a 0.2 μm filtered solution containing PBS, 5% mannitoland 0.01% Tween 80, pH 7.4
AA Sequence
VPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM

UniProtKB · P05231

Interleukin-6

IL6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P05231
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IL-6
EC number
—
Processing
Precursor
Secondary accessions
Q9UCU2, Q9UCU3, Q9UCU4
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Acute phase

Molecular function

CytokineGrowth factor

PTM

Disulfide bondGlycoproteinPhosphoprotein

Cellular component

Secreted

Domain

Signal

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