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Human ACVR2A Protein, hFc Tag

CAT: 0013-GTR19062753-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19062753-01Size:10 µg
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Description
Recombinant human ACVR2A Protein with C-terminal human Fc tag
Product Name Alternative
ACVR2; ACTRII
UniProt
P27037
Expression Region
ACVR2A (Ala20-Pro135) hFc (Glu99-Ala330)
Reactivity
Human
Conjugation
Unconjugated
Tag
C-Human Fc tag
Source
Mammalian
Field of Research
Signal Transduction
Purity
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Form
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Molecular Weight
The protein has a predicted molecular mass of 39.5 kDa after removal of the signal peptide. The apparent molecular mass of ACVR2A-hFc is approximately 55-70 kDa due to glycosylation.
Storage Conditions
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.
Notes
For research use only.

UniProtKB · P27037

Activin receptor type-2A

AVR2A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P27037
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ACVR2A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.30
Processing
Precursor
Secondary accessions
B2RAB8, B4DWQ2, D3DP85, Q53TH4, Q6NWV2, Q92474
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMagnesiumManganeseMetal-bindingNucleotide-binding

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoprotein

Molecular function

KinaseReceptorSerine/threonine-protein kinaseTransferase

Domain

SignalTransmembraneTransmembrane helix

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