Anti-MINDY3 Antibody Picoband®, Dylight594 Conjugate

• Background:

  The protein encoded by this gene contains a caspase-associated recruitment domain and may function in apoptosis. It has been identified as a tumor suppressor in lung and gastric cancers, and a polymorphism in the gene may be associated with gastric cancer risk. Alternative splicing of this gene results in multiple transcript variants.

• Description:

  Boster Bio Anti-MINDY3 Antibody Picoband® catalog # A32140-1. Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

• Synonyms:

  Protein Bop; BH3-only protein; Retrotransposon Gag-like protein 10; RTL10; BOP, C22orf29

• Gene Name:

  retrotransposon Gag like 10

• Gene ID:

  80013

• UniProt:

  Q9H8M7

• Host:

  Rabbit

• Reactivity:

  Human,Monkey,Mouse,Rat

• Cross Reactivity:

  No cross-reactivity with other proteins.

• Immunogen:

  E.coli-derived human MINDY3 recombinant protein (Position: A52-K396).

• Clonality:

  Polyclonal

• Tissue Specificity:

  Ubiquitously expressed.

• Applications:

  WB,ICC,IF,Flow Cytometry,ELISA

• Purification:

  Immunogen affinity purified.

• Concentration:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Form:

  Lyophilized

• Reconstitution:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Function:

  Could induce apoptosis in a BH3 domain-dependent manner. The interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity.

• Components:

  Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

• References & Citations:

  1. Liu, B., Liu, Y., Chen, J., Wei, Z., Yu, H., Zhen, Y., Lu, L., Hui, R. CARP is a novel caspase recruitment domain containing pro-apoptotic protein. Biochem. Biophys. Res. Commun. 293: 1396-1404, 2002. 2. Shi, Y., Chen, J., Li, Z., Zhang, Z., Yu, H., Sun, K., Wang, X., Song, X., Wang, Y., Zhen, Y., Yang, T., Lou, K., Zhang, Y., Zhang, G., Hu, Y., Ji, J., Hui, R. C10ORF97 is a novel tumor-suppressor gene of non-small-cell lung cancer and a functional variant of this gene increases the risk of non-small-cell lung cancer. Oncogene 30: 4107-4117, 2011.

• Storage Conditions:

  At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

• Calculated Molecular Weight:

  14377 MW

• Observed Molecular Weight:

  50 kDa

• Fragment:

  Rabbit IgG

• Applications Notes:

  Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat, Monkey
  Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
  Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
  ELISA, 0.1-0.5 μg/ml, -
  

• Subcellular Location:

  Cell membrane; Lipid-anchor, GPI-anchor.

• Protein Name:

  Lymphocyte antigen 6A-2/6E-1