Anti-IFNGR1 Antibody Picoband® (Dylight594 Conjugate)

• Background:

  Interferon gamma receptor 1 (IFNGR1), also known as CD119 (Cluster of Differentiation 119), is a protein that in humans is encoded by the IFNGR1 gene. This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

• Description:

  Boster Bio Anti-IFNGR1 Antibody Picoband® catalog # A01716-1. Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

• Synonyms:

  Interferon gamma receptor 1;IFN-gamma receptor 1;IFN-gamma-R1;CDw119;CD119;IFNGR1;

• Gene Name:

  Interferon gamma receptor 1

• UniProt:

  P15260

• Host:

  Rabbit

• Reactivity:

  Human

• Cross Reactivity:

  No cross-reactivity with other proteins.

• Immunogen:

  A synthetic peptide corresponding to a sequence at the C-terminus of human IFNGR1, different from the related mouse sequence by seventeen amino acids.

• Clonality:

  Polyclonal

• Tissue Specificity:

  Liver and small intestine. Also found in ovary, testis and kidney.

• Applications:

  Flow Cytometry,IHC,ICC,WB

• Purification:

  Immunogen affinity purified.

• Concentration:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Form:

  Lyophilized

• Reconstitution:

  Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

• Function:

  Associates with IFNGR2 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:2971451, PubMed:7617032, PubMed:10986460). Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:7673114). .

• Storage Conditions:

  Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

• Fragment:

  Rabbit IgG

• Applications Notes:

  Immunohistochemistry (Frozen Section), 0.5-1μg/ml
  Immunocytochemistry, 0.5-1μg/ml
  Western blot, 0.1-0.5μg/ml
  Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells
  

• Subcellular Location:

  Cell membrane ; Single-pass type I membrane protein .

• Protein Name:

  Interferon gamma receptor 1