Anti-ITPKC Antibody Picoband®, Dylight550 Conjugate

• Background:

  This gene encodes a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.

• Description:

  Boster Bio Anti-ITPKC Antibody Picoband® catalog # A07845-1. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

• Gene Name:

  ITPKC

• Gene ID:

  80271

• UniProt:

  Q96DU7

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  E.coli-derived human ITPKC recombinant protein (Position: D292-E607). Human ITPKC shares 88.1% and 88% amino acid (aa) sequence identity with mouse and rat ITPKC, respectively.

• Clonality:

  Polyclonal

• Applications:

  ELISA,Flow Cytometry,WB

• Purification:

  Immunogen affinity purified.

• Concentration:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Form:

  Lyophilized

• Reconstitution:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Components:

  Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

• References & Citations:

  1. Chi, H., Huang, F.-Y., Chen, M.-R., Chiu, N.-C., Lee, H.-C., Lin, S.-P., Chen, W.-F., Lin, C.-L., Chan, H.-W., Liu, H.-F., Huang, L.-M., Lee, Y.-J. ITPKC gene SNP rs28493229 and Kawasaki disease in Taiwanese children. Hum. Molec. Genet. 19: 1147-1151, 2010. 2. Dewaste, V., Pouillon, V., Moreau, C., Shears, S., Takazawa, K., Erneux, C. Cloning and expression of a cDNA encoding human inositol 1,4,5-trisphosphate 3-kinase C. Biochem. J. 352: 343-351, 2000. 3. Hamosh, A. Personal Communication. Baltimore, Md. 5/6/2020.

• Storage Conditions:

  At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

• Calculated Molecular Weight:

  75 kDa

• Observed Molecular Weight:

  100 kDa

• Applications Notes:

  Western blot, 0.25-0.5 μg/ml, Human
  Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
  ELISA, 0.1-0.5 μg/ml, -