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Thonzylamine

CAT: 0804-HY-B1317-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1317-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Thonzylamine is an orally active H1 histamine receptor antagonist with good antihistaminic and antianaphylactic properties. Thonzylamine can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases[1][2].
CAS Number
91-85-0
Product Name Alternative
Neohetramine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/thonzylamine.html
Purity
98.03
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN(C)CCN(CC1=CC=C(OC)C=C1)C2=NC=CC=N2
Molecular Formula
C16H22N4O
Molecular Weight
286.37
Precautions
H302, H315, H319, H335
References & Citations
[1]AARON TH, et, al. Neohetramine and thephorin; two new antihistaminic drugs. Can Med Assoc J. 1948 Nov; 59 (5) : 438-41.|[2]Zhou S, et, al. Design, synthesis and biological activity of a novel ethylenediamine derivatives as H 1 receptor antagonists. Bioorg Med Chem. 2019 Dec 15; 27 (24) : 115127.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
H1 Receptor

Alternative Products

CatalogName
S6469-01Thonzylamine
BA5440-25Thonzylamine (Standard)
AR-T01899-01Thonzylamine Hydrochloride
TRC-N703555-100MGN-Nitroso Desmethyl-thonzylamine
CS-O-50065N-Nitroso Desmethyl Thonzylamine

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