Gly-Mal-GGFG-Deruxtecan 2-hydroxypropanamide

Gly-Mal-GGFG-Deruxtecan 2-hydroxypropanamide

• CAS Number: 2750623-07-3
• UNSPSC Description: Gly-Mal-GGFG-Deruxtecan 2-hydroxy propionamide is a camptothecin-deriver and can be used as a drug linker for ADC.
• Target Antigen: Drug-Linker Conjugates for ADC; Topoisomerase
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/gly-mal-ggfg-deruxtecan-2-hydroxypropanamide.html
• Solubility: 10 mM in DMSO
• Smiles: OC(CNC[C@H](N1C(C=CC1=O)=O)C(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCO[C@@H](C)C(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O)=O
• Molecular Weight: 1079.05
• References & Citations: [1]Zhu Yi, et al. Camptothecin derivative and ligand-drug conjugate thereof. WO2022078260A1. 2021.
• Shipping Conditions: Dry Ice
• Clinical Information: No Development Reported