Anti-Adenylate Kinase 1/AK1 Antibody Picoband® (Dylight488 Conjugate)

• Background:

  This gene encodes an adenylate kinase enzyme involved in energy metabolism and homeostasis of cellular adenine nucleotide ratios in different intracellular compartments. This gene is highly expressed in skeletal muscle, brain and erythrocytes. Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

• Description:

  Boster Bio Anti-Adenylate Kinase 1/AK1 Antibody Picoband® catalog # PB10033. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

• Synonyms:

  Adenylate kinase isoenzyme 1 ;AK 1 ;2.7.4.3 ;2.7.4.6 ;ATP-AMP transphosphorylase 1 ;ATP:AMP phosphotransferase ;Adenylate monophosphate kinase ;Myokinase ;AK1 ;

• Gene Name:

  Adenylate kinase isoenzyme 1

• UniProt:

  P00568

• Host:

  Rabbit

• Reactivity:

  Human,Mouse,Rat

• Cross Reactivity:

  No cross-reactivity with other proteins.

• Immunogen:

  A synthetic peptide corresponding to a sequence at the C-terminus of human Adenylate Kinase 1, different from the related mouse sequence by seven amino acids, and from the related rat sequence by four amino acids.

• Clonality:

  Polyclonal

• Tissue Specificity:

  Widely expressed. Highest level in placenta, liver, muscle and kidney.

• Applications:

  Flow Cytometry,IHC,WB

• Purification:

  Immunogen affinity purified.

• Concentration:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Form:

  Lyophilized

• Reconstitution:

  Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

• Function:

  Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. .

• Storage Conditions:

  Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

• Fragment:

  Rabbit IgG

• Applications Notes:

  Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
  Immunohistochemistry, 2-5μg/ml, Human, Mouse, Rat
  Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Human

• Subcellular Location:

  Cytoplasm.

• Protein Name:

  Adenylate kinase isoenzyme 1