Anti-MIPOL1 Antibody Picoband®, Cy3 Conjugate

• Background:

  MIPOL1 (Mirror Image Polydactyly 1), also known as CCDC193 (Coiled-coil domain containing 193), is a protein that in humans is encoded by the MIPOL1 gene. This gene encodes a coiled-coil domain-containing protein. The encoded protein may function as a tumor suppressor. A translocation that results in truncation of the protein encoded by this locus has been associated with mirror-image polydactyly, also known as Laurin-Sandrow Syndrome. Alternatively spliced transcript variants have been described.

• Description:

  Boster Bio Anti-MIPOL1 Antibody Picoband® catalog # A11968-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

• Synonyms:

  Solute carrier family 2, facilitated glucose transporter member 6; Glucose transporter type 6; GLUT-6; Glucose transporter type 9; GLUT-9; SLC2A6; GLUT9

• Gene Name:

  solute carrier family 2 member 6

• Gene ID:

  145282

• UniProt:

  Q8TD10

• Host:

  Rabbit

• Reactivity:

  Human,Mouse,Rat

• Cross Reactivity:

  No cross-reactivity with other proteins.

• Immunogen:

  E.coli-derived human MIPOL1 recombinant protein (Position: N63-A399).

• Clonality:

  Polyclonal

• Tissue Specificity:

  Highly expressed in brain, spleen and peripheral blood leukocytes.

• Applications:

  WB,Flow Cytometry,ELISA

• Purification:

  Immunogen affinity purified.

• Concentration:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Form:

  Lyophilized

• Reconstitution:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Function:

  Facilitative glucose transporter; binds cytochalasin B with low affinity.

• Components:

  Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

• References & Citations:

  1. Kamnasaran, D., O'Brien, P. C., Zackai, E. H., Muenke, M., Ferguson-Smith, M. A., Cox, D. W. Rearrangement in the PITX2 and MIOL1 genes in a patient with a t(4;14) chromosome. Europ. J. Hum. Genet. 11: 315-324, 2003. 2. Kondoh, S., Sugawara, H., Harada, N., Matsumoto, N., Ohashi, H., Sato, M., Kantaputra, P. N., Ogino, T., Tomita, H., Ohta, T., Kishino, T., Fukushima, Y., Niikawa, N., Yoshiura, K. A novel gene is disrupted at a 14q13 breakpoint of t(2;14) in a patient with mirror-image polydactyly of hands and feet. J. Hum. Genet. 47: 136-139, 2002.

• Storage Conditions:

  At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

• Observed Molecular Weight:

  52 kDa

• Fragment:

  Rabbit IgG

• Applications Notes:

  Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
  Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
  ELISA, 0.1-0.5 μg/ml, -
  

• Subcellular Location:

  Cell membrane. Multi-pass membrane protein.