Anti-HCLS1 Antibody Picoband®, Cy3 Conjugate

• Background:

  Hematopoietic lineage cell-specific protein is a protein that in humans is encoded by the HCLS1 gene. Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and protein kinase binding activity. Involved in several processes, including positive regulation of intracellular signal transduction; positive regulation of protein phosphorylation; and regulation of transcription, DNA-templated. Located in cytosol; nucleus; and plasma membrane. Part of transcription regulator complex.

• Description:

  Boster Bio Anti-HCLS1 Antibody Picoband® catalog # A04313-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

• Synonyms:

  Interleukin-3 receptor subunit alpha; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA; CD123; IL3RA; IL3R

• Gene Name:

  interleukin 3 receptor subunit alpha

• Gene ID:

  3059

• UniProt:

  P14317

• Host:

  Rabbit

• Reactivity:

  Human

• Cross Reactivity:

  No cross-reactivity with other proteins.

• Immunogen:

  E.coli-derived human HCLS1 recombinant protein (Position: N213-K473).

• Clonality:

  Polyclonal

• Tissue Specificity:

  Brain.

• Applications:

  WB,Flow Cytometry,ELISA

• Purification:

  Immunogen affinity purified.

• Concentration:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Form:

  Lyophilized

• Reconstitution:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Function:

  This is a receptor for interleukin-3.

• Components:

  Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

• References & Citations:

  1. Egashira, M., Kitamura, D., Watanabe, T., Niikawa, N. The human HCLS1 gene maps to chromosome 3q13 by fluorescence in situ hybridization. Cytogenet. Cell Genet. 72: 175-176, 1996. 2. Kitamura, D., Kaneko, H., Miyagoe, Y., Ariyasu, T., Watanabe, T. Isolation and characterization of a novel human gene expressed specifically in the cells of hematopoietic lineage. Nucleic Acids Res. 17: 9367-9379, 1989. 3. Scielzo, C., Ghia, P., Conti, A., Bachi, A., Guida, G., Geuna, M., Alessio, M., Caligaris-Cappio, F. HS1 protein is differentially expressed in chronic lymphocytic leukemia patient subsets with good or poor prognoses. J. Clin. Invest. 115: 1644-1650, 2005.

• Storage Conditions:

  At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

• Observed Molecular Weight:

  75 kDa

• Fragment:

  Rabbit IgG

• Applications Notes:

  Western blot, 0.25-0.5 μg/ml, Human
  Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
  ELISA, 0.1-0.5 μg/ml, -
  

• Subcellular Location:

  Membrane. Single-pass type I membrane protein.