Anti-Epigen/Epgn Antibody Picoband® (Biotine Conjugate)

• Background:

  Epigen also known as epithelial mitogen is a protein that in humans is encoded by the EPGN gene. The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate.

• Description:

  Boster Bio Anti-Epigen/Epgn Antibody Picoband® catalog # A10011-2. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

• Synonyms:

  Epigen;Epithelial mitogen;EPG;Epgn;

• Gene Name:

  Epigen

• UniProt:

  Q924X1

• Host:

  Rabbit

• Reactivity:

  Mouse,Rat

• Cross Reactivity:

  No cross-reactivity with other proteins.

• Immunogen:

  E. coli-derived mouse Epigen recombinant protein (Position: A19-K109). Mouse Epigen shares 82.8% amino acid (aa) sequence identity with human Epigen.

• Clonality:

  Polyclonal

• Applications:

  ELISA,IHC,WB

• Purification:

  Immunogen affinity purified.

• Concentration:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Form:

  Lyophilized

• Reconstitution:

  Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

• Function:

  Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.

• Storage Conditions:

  Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

• Fragment:

  Rabbit IgG

• Applications Notes:

  Western blot, 0.1-0.5μg/ml, Mouse, Rat
  Immunohistochemistry, 2-5 μg/ml, Mouse, Rat
  ELISA, 0.1-0.5μg/ml, -
  

• Subcellular Location:

  Membrane ; Single-pass type I membrane protein .