Anti-IFT43 Antibody Picoband®

• Background:

  This gene encodes a subunit of the intraflagellar transport complex A (IFT-A) . IFT-A is a multiprotein complex that plays an important role in cilia assembly and maintenance by mediating retrograde ciliary transport. Mutations in this gene are a cause of cranioectodermal dysplasia-3 (CED3), also known as Sensenbrenner syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

• Description:

  Boster Bio Anti-IFT43 Antibody Picoband® catalog # A10264. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

• Synonyms:

  Pre T-cell antigen receptor alpha; pT-alpha; pTa; pT-alpha-TCR; PTCRA

• Gene Name:

  Pre T cell antigen receptor alpha

• UniProt:

  Q96FT9

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Cross Reactivity:

  No cross-reactivity with other proteins.

• Immunogen:

  E.coli-derived human IFT43 recombinant protein (Position: M1-T208) .

• Clonality:

  Polyclonal

• Tissue Specificity:

  Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.

• Applications:

  WB, ICC, IF, Flow Cytometry, ELISA

• Field of Research:

  Hematopoietic Progenitors, Lymphoid, Stem Cells, T Lymphocytic Lineage

• Purification:

  Immunogen affinity purified.

• Concentration:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Form:

  Lyophilized

• Reconstitution:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Function:

  The pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) regulates early T-cell development. .

• Storage Conditions:

  At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

• Fragment:

  Rabbit IgG

• Applications Notes:

  Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
  Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
  Flow Cytometry (Fixed), 1-3 μg/1x10^6 cells, Human
  ELISA, 0.1-0.5 μg/ml, -
  

• Other Gene Names:

  IFT43

• Subcellular Location:

  Membrane; Single-pass type I membrane protein.

• Protein Name:

  Protein NDRG3