Recombinant Human TNFRSF1A

• Description:

  A member of the TNFR superfamily, it is one of the major receptors for tumor necrosis factor-alpha (TNFα). Binding of either TNF-α or TNF-β to TNFRSF1A starts a signal transduction pathway that results in the activation of the transduction factor NF-κB, whose target genes are involved in the regulation of inflammatory responses, and, in certain cells induce apoptosis.

• Gene Name:

  TNFRSF1A

• Gene Aliases:

  Soluble Tumor Necrosis Factor Type I, TNFRSF1A, TNFAR, TNF-R55, TNFR60, p55, CD120a

• Gene ID:

  7132

• Accession Number:

  P19438

• Organism:

  Human

• Source:

  E. coli

• Concentration:

  <1.0 EU/μg of recombinant protein as determined by the LAL method.

• Purity:

  >95% as determined by SDS-PAGE

• Solubility:

  A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

• Molecular Weight:

  18.4

• Shipping Conditions:

  Ambient Temperature

• Storage Conditions:

  The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

• Appearance:

  Lyophilized Powder

• Formulation:

  coming soon