Anti-Cyclin H CCNH Monoclonal Antibody

• Description:

  Boster Bio Anti-Cyclin H CCNH Monoclonal Antibody catalog # M03013-2. Tested in WB applications. This antibody reacts with Canine, Human, Mouse, Rat, Swine.

• Synonyms:

  Cyclin-H; MO15-associated protein; p34; p37; CCNH;

• Gene Name:

  CCNH

• UniProt:

  P51946

• Host:

  Mouse

• Reactivity:

  Human, Mouse, Rat, Canine, Swine

• Immunogen:

  Purified recombinant human Cyclin H protein fragments expressed in E.coli.

• Clonality:

  Monoclonal

• Applications:

  WB

• Purification:

  Affinity purification

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:1000-1:2000

• Form:

  Liquid

• Function:

  Regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

• Molecular Weight:

  37643 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Cyclin-H

• Subcellular Location:

  Nucleus.

• Protein Name:

  Cyclin-H