Products for Research Use Only
RegisterLogin

NK3201

CAT: 0804-HY-12514Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-12514Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NK3201 is an orally active chymase inhibitor (IC50: 2.5, 1.2, and 28 nM for human, dog and hamster chymase). NK3201 inhibits Bleomycin -induced pulmonary fibrosis. NK3201 inhibits vascular proliferation in grafted vein[1][2].
CAS Number
204460-24-2
UNSPSC
12352005
Target
Ser/Thr Protease
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Assay Protocol
https://www.medchemexpress.com/nk3201.html
Smiles
O=C(NC(CC1=CC=CC=C1)C(C(CCCOC2=NC=CC=C2)=O)=O)CN(C(C3=CC=CC=C3)=NC=C4NC=O)C4=O
Molecular Formula
C31H29N5O6
Molecular Weight
567.59
References & Citations
[1]Sakaguchi M, et al. A specific chymase inhibitor, NK3201, suppresses bleomycin-induced pulmonary fibrosis in hamsters. Eur J Pharmacol. 2004 Jun 16;493 (1-3) :173-6. |[2]Takai S, et al. Oral administration of a specific chymase inhibitor, NK3201, inhibits vascular proliferation in grafted vein. Life Sci. 2001 Aug 31;69 (15) :1725-32.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
MBS5777870NK3201

Popular Products