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Anti-PARD3A Antibody

CAT: 0519-A01897-1Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A01897-1Size:100 µL
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Description
Boster Bio Anti-PARD3A Antibody catalog # A01897-1. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Partitioning defective 3 homolog; PAR-3; PARD-3; Atypical PKC isotype-specific-interacting protein; ASIP; CTCL tumor antigen se2-5; PAR3-alpha; PARD3
Gene Name
PARD3
UniProt
Q8TEW0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human PARD3. AA range:1141-1190
Clonality
Polyclonal
Tissue Specificity
Widely expressed.
Applications
ELISA, IF, IHC, WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Function
Adapter protein involved in asymmetrical cell division and cell polarization processes (PubMed:27925688, PubMed:10954424) . Seems to play a central role in the formation of epithelial tight junctions (PubMed:27925688) . Targets the phosphatase PTEN to cell junctions (By similarity) . Involved in Schwann cell peripheral myelination (By similarity) . Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly (By similarity) . The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (PubMed:10934474) . Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons (PubMed:19812038, PubMed:27925688) .
Molecular Weight
151423 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Partitioning defective 3 homolog
Subcellular Location
Cytoplasm . Endomembrane system
Protein Name
Partitioning defective 3 homolog

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