Anti-ARRDC3 Antibody

• Description:

  Boster Bio Anti-ARRDC3 Antibody catalog # A07177-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Arrestin domain-containing protein 3; TBP-2-like inducible membrane protein

• Gene Name:

  ARRDC3

• UniProt:

  Q96B67

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human ARRDC3. AA range:365-414

• Clonality:

  Polyclonal

• Tissue Specificity:

  Highly expressed in skeletal muscle, placenta, kidney, lung, liver, blood, adrenal gland, lymph node, mammary gland, thyroid, and trachea (PubMed:16269462, PubMed:21982743) . Very low levels in colon, thymus, spleen, small intestine, bladder and bone marrow (PubMed:16269462) . Strong expression in differentiated adipocytes compared to preadipocytes (PubMed:16269462) . Detected in omental fat and subcutaneous fat tissue (PubMed:21982743) .

• Applications:

  WB, IHC, ELISA

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Form:

  Liquid

• Function:

  Adapter protein that plays a role in regulating cell- surface expression of adrenergic receptors and probably also other G protein-coupled receptors (PubMed:20559325, PubMed:21982743, PubMed:23208550) . Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation (PubMed:20559325, PubMed:23208550) . May recruit NEDD4 to ADRB2 (PubMed:20559325) . Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes (PubMed:23208550) .

• Molecular Weight:

  46395 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG

• Other Gene Names:

  Arrestin domain-containing protein 3

• Subcellular Location:

  Cytoplasm

• Protein Name:

  Arrestin domain-containing protein 3